Ships within 27 hours (on average).
Ships within 27 hours (on average).
20-Hydroxyecdysone(ecdysteroneor20E) is a naturally occurringecdysteroidhormonewhich controls theecdysis(moulting) andmetamorphosisofarthropods. It is therefore one of the most common moulting hormones in insects, crabs, etc. It is also aphytoecdysteroidproduced by various plants, includingCyanotis vaga,Ajuga turkestanicaandRhaponticum carthamoideswhere its purpose is presumably to disrupt thedevelopmentandreproductionof insect pests. In arthropods, 20-hydroxyecdysone acts through theecdysone receptor. Although mammals lack thisreceptor, 20-hydroxyecdysone may affectmammalian(includinghuman) biological systemsin vitro, but there is uncertainty whether anyin vivoor physiological effects occur. 20-Hydroxyecdysone is an ingredient of some supplements that aim to enhance physical performance. In humans it binds to theestrogen receptor beta(ERβ) protein-coding gene.
20-Hydroxyecdysone and other ecdysteroids are marketed as ingredients in nutritional supplements for various sports, particularlybodybuilding.A comprehensive study, designed to find any strength or athletic improvement from 20-hydroxyecdysone, was published in 2006. The study looked for improvement in actual exercises performed and tested for improvements/increases in chemical indicators such as body composition and free/available testosterone. The results of the 2006 study concluded that using 30mg per day of 20-hydroxyecdysone administered orally did not significantly affect anabolic or catabolic responses to resistance training, body composition, or training adaptations.However, a number of earlier studies supported the anabolic effects of 20-Hydroxyecdysone. A more recent study conducted in 2019 by a team that included the Department for Molecular and Cellular Sports Medicine at theGerman Sport University Cologne, found that significantly higher increases in muscle mass were observed in participants dosed with ecdysterone, with significantly more pronounced increases in one-repetition bench press performance.The study was funded by theWorld Anti-Doping Agency(WADA) and demonstrated a significant dose-responsive anabolic effect of 20-Hydroxyecdysone supplementation on athletes during resistance training. Furthermore, recent studieshave elucidated that the mechanism of action of 20-Hydroxyecdysone on human muscle cells is relatively selective activation of the beta form of the estrogen receptor (ERβ), which is known to result in muscle hypertrophy.
Each capsule contains 250mg UV95% Ecdysterones, 5mg Black Pepper Extract for better absorption.
Read more on Beta Ecdysterone here
| Updated: 7th February 2023
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